The Breakthrough

Perioimm has developed and patented a new genetic test for periodontal disease susceptibility, based on whether an individual’s innate immunity to oral bacteria is strong or weak. Weak innate immunity is indicated by genes previously associated with moderate and severe periodontal disease and recently also in patients with diseases of old age such as cardiovascular disease, arthritis, and dementia.

Journal Article

Innate Immunity Genes and Periodontitis Susceptibility

Patent

DEVICES, KITS, AND METHODS FOR DETERMINING INCREASED SUSCEPTIBILITY TO AND TREATMENT AND PREVENTION OF PERIODONTITIS, ALZHEIMER'S DISEASE, AND OTHER CONDITIONS

Patent Abstract

Diagnostic microarray devices, kits, and methods of treating or reducing the occurrence of various conditions or diseases are disclosed, wherein the conditions or diseases include (but are not limited to) periodontal disease, Alzheimer's disease, cardiovascular disease, arthritis, and adverse pregnancy outcomes. The devices, kits, and methods utilize an analysis of single nucleotide polymorphisms (SNPs) from various interleukins.